Pizo Electric Translator
Pizo Electric Translator - Related Videos
02:33
Initiation of Translation
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2020
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs. First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
01:44
Termination of Translation
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2020
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
10:28
Open-Source Real-Time Closed-Loop Electrical Threshold Tracking for Translational Pain Research
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Cited by 5 •
2023
APTrack is a software plugin developed for the Open Ephys platform that enables real-time data visualization and the closed-loop electrical threshold tracking of neuronal action potentials. We have successfully used this in microneurography for human C-fiber nociceptors and mouse C-fiber and Aδ-fiber nociceptors.
06:50
Electric Potential
0 Views •
2023
Source: Yong P. Chen, PhD, Department of Physics & Astronomy, College of Science, Purdue University, West Lafayette, IN Electric potential, also known as "voltage", measures the electric potential energy per unit charge. Electric field is a scalar quantity and is fundamental to many electrical effects. Like potential energy, what is physically meaningful is the difference in the electric potential. For example, the spatial variation in the electric potential is related to the electric...
02:07
Improving Translational Accuracy
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2020
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
FAQs
Control begins with the applied voltage: the resulting electric field changes the dimensions of the piezoelectric material, producing a corresponding mechanical displacement. Adjusting the electrical input therefore provides a way to regulate movement with high precision. This voltage-to-motion relationship is central when an instrument must position components accurately rather than move them broadly.
The same material also supports the reverse measurement pathway: mechanical deformation can generate an electrical signal. This bidirectional behavior allows a piezoelectric translator to participate not only in actuation, but also in detecting deformation-related changes. In experimental systems, that principle helps connect controlled mechanical movement with electrical monitoring of the device's physical response.
Three characteristics determine its practical value: rapid response, fine resolution, and compact design. Rapid response supports timely movement, fine resolution supports very small positional adjustments, and compactness makes integration easier where instrument space is limited. Together, these properties improve control of experiments that combine delicate samples, small fluid volumes, or tightly constrained hardware.
In an automated drug-delivery system, operation centers on applying a selected voltage and using the resulting displacement to position the delivery component. The translator can therefore provide controlled movement during handling of pharmaceutical formulations or biological samples. Its fine resolution and rapid response are especially relevant when the system must manage small fluid volumes with consistent positioning.
Microfluidic instruments work with very small fluid volumes, so unintended positional changes can affect handling and measurement. Integrating a piezoelectric translator provides fine mechanical adjustment in a compact format, while its rapid response supports responsive instrument operation. In pharmacology, this can improve control and reproducibility when researchers manipulate pharmaceutical formulations or biological samples in microscale workflows.
Microscopy platforms and screening equipment benefit from precise movement because measurements depend on controlled positioning of samples or instrument components. A piezoelectric translator supplies rapid, fine adjustments without requiring a large mechanical assembly. In pharmacological studies, this supports more consistent examination of biological samples and more reproducible screening workflows, particularly when automated equipment must repeat small positional changes.