Normal Saline Flush

A normal saline flush is the instillation of sterile 0.9% sodium chloride solution through an intravenous catheter or vascular access device to maintain patency and support safe medication delivery. The solution clears residual medication, blood, or other material from the lumen, while controlled injection helps confirm that the catheter remains open and usable. In clinical practice, healthcare professionals may flush peripheral or central lines before and after medication administration, infusions, or blood sampling, following device-specific protocols. Proper flushing can reduce catheter occlusion, limit medication incompatibility within the line, and help identify resistance or other access problems early.

Normal Saline Flush - Related Videos

Education

JoVE Science Education - Clinical Skills

Assessing and Flushing a Peripheral Intravenous Line

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2023

Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT After peripheral intravenous (IV) access is initiated, it is important to assess and maintain the IV catheter according to institutional policies and nursing standards of practice. The regular assessment of the insertion site and the surrounding areas for signs of complications is necessary to prevent IV catheter complications, including infiltration, phlebitis, infection, extravasation, or...

Research

JoVE EoE - Neuropathology

A Hypertonic Saline Injection Technique for Inducing Glaucoma in Rats

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2025

This video demonstrates glaucoma induction in an anesthetized rat by injecting hypertonic saline into the episcleral vein. The saline enters the trabecular meshwork via Schlemm's canal, causing tissue scarring, which blocks aqueous humor outflow and raises intraocular pressure. The elevated pressure damages retinal ganglion cells, leading to glaucoma.

Salinity Tolerance of Alishewanella Species Isolated from Seawall Muddy Water

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2025

Begin with a culture of Alishewanella, a Gram-negative, salt-tolerant bacterium.Next, streak the culture onto agar plates containing increasing concentrations of sodium chloride to simulate varying levels of saline stress.Overlay each plate with a layer of unsolidified medium to prevent oxygen diffusion and maintain the culture in an oxygen-limited environment.Seal and incubate the plates at an optimum temperature to support bacterial growth.During incubation, the bacterium exhibits varying...

Salinity-dependent Toxicity Assay of Silver Nanocolloids Using Medaka Eggs

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Cited by 2 •

2016

Embryonic stages are the most susceptible to xenobiotics. Although chemical toxicity depends on salinity, no method exists to test the salinity dependence of toxicity to aquatic organisms. Here, we describe a new and high-throughput method for determining the salinity dependence of toxicity to aquatic embryos.

Normal Stress

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2024

Normal stress is a type of stress that occurs when forces act perpendicular, or normal, to a material's cross-sectional area. This stress often arises in structures when subjected to axial loading, which is the application of force along the axis of an object. A practical example of this can be found in bridge truss members. When a rod is under axial loading, the internal forces and corresponding stress are normal to the plane of the section, so it is termed normal stress. It's important to...

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