Intraoperative Hemorrhage

Intraoperative hemorrhage is excessive bleeding that occurs during a surgical procedure, posing immediate risks to tissue perfusion, oxygen delivery, and patient stability. It develops when surgical injury disrupts blood vessels and the body’s coagulation response cannot contain blood loss, with severity influenced by the vessel involved, underlying disease, medications, and the operation itself. Recognition relies on continuous observation of the operative field, blood-loss estimation, and hemodynamic and laboratory monitoring. Prompt control through surgical hemostasis, fluid and blood-product replacement, and correction of coagulation abnormalities can limit complications and guide safer perioperative care.

Intraoperative Hemorrhage - Related Videos

Research

JoVE Journal - Medicine

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

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Cited by 12 •

2016

In early gastric cancer, the aim of surgery is to precisely remove the distal stomach including the primary tumor. To do this, accurate localization of the tumor is crucial, especially in totally laparoscopic surgery. This protocol describes a procedure for intraoperative gastroscopy in totally laparoscopic subtotal gastrectomy.

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

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Cited by 3 •

2009

Description of the surgical obliteration of a cerebral aneurysm utilizing an ultrasonic flow probe to assess arterial flow prior to and after aneurysm clip placement.

Modeling Drug-Induced Hemorrhage in Zebrafish Larva

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2025

In this video, fertilized zebrafish embryos are dechorionated under a stereo microscope and then exposed to a cholesterol synthesis inhibitor, leading to the development of blood vessel ruptures and brain hemorrhages in the larvae. Hemorrhagic larvae, identifiable by distinct red spots, are subsequently separated under a microscope for further analysis.

Integrated Compensatory Responses in a Human Model of Hemorrhage

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Cited by 11 •

2016

The purpose of this protocol is to demonstrate the techniques for measuring compensatory responses to reduced central blood volume using lower body negative pressure as a noninvasive experimental model of human hemorrhage which can be used to quantify the total integration of compensatory mechanisms to blood volume deficit in humans.

Intraoperative Ultrasound in Spinal Surgery

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2022

Here, we present a protocol on the use of intraoperative ultrasound in spinal surgery, particularly in cases of intradural lesions and lesions in the ventral spinal canal when using a posterior approach.

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