Optic Lobe

The optic lobe is a visual-processing region of the brain, especially well characterized in insects and other arthropods, where it transforms retinal signals into neural representations of the surrounding environment. Photoreceptors transmit information through layered neuropils, including the lamina, medulla, and lobula, whose retinotopic circuits extract features such as contrast, motion, and spatial patterns. Studying the optic lobe reveals how neural circuits encode visual information and guide behavior. Its relatively accessible organization makes it a valuable model for investigating synaptic processing, sensory integration, neural computation, and the evolution of vision in neuroscience.

Optic Lobe - Related Videos

Research

JoVE Journal - Neuroscience

Hybridization Chain Reaction FISH in the Developing Drosophila Optic Lobe

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2026

This protocol describes the steps required to perform hybridization chain reaction fluorescent in situ hybridization (HCR-FISH) in Drosophila melanogaster larval optic lobes. Procedures for probe design, hybridization, amplification, and tissue mounting are detailed to facilitate visualization of the developing optic lobe.

Individual Lobe Extraction from Prostate: A Technique to Harvest Individual Prostate Lobes from Mouse Prostate

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2023

This video describes a technique to harvest individual lobes from the prostate gland of a mouse model. Individual lobes can then be used for histological analysis and cancer research.

Dissection, Immunohistochemistry and Mounting of Larval and Adult Drosophila Brains for Optic Lobe Visualization

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Cited by 5 •

2021

This protocol describes three steps to prepare larval and adult Drosophila optic lobes for imaging: 1) brain dissections, 2) immunohistochemistry and 3) mounting. Emphasis is placed on step 3, as distinct mounting orientations are required to visualize specific optic lobe...

Education

JoVE Core - Introduction to Psychology

Lobes of the Cerebrum

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2024

The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities. Frontal lobe The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements.

A Comprehensive Protocol for Manual Segmentation of the Medial Temporal Lobe Structures

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Cited by 33 •

2014

The present work provides a comprehensive set of guidelines for manually tracing the medial temporal lobe (MTL) structures. This protocol can be applied to research involving structural and/or combined structural-functional magnetic resonance imaging (MRI) investigations of the MTL, in both healthy and clinical groups.

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