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JoVE Journal
Biology

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Aortic Ring Assay
 

Aortic Ring Assay

Article DOI: 10.3791/1564
November 24th, 2009

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Summary November 24th, 2009

Angiogenesis, the sprouting of blood vessels from pre-existing vasculature, is associated with both natural and pathological processes. Here we demonstrate an aortic ring assay that allows angiogenic potentiators and inhibitors to be directly added to aortic rings in culture. Sprouting and neovessel outgrowth can be determined by inspecting the aortic rings over a period of 6-12 days.

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