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JoVE Journal
Immunology and Infection

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Comparative in vivo Study of gp96 Adjuvanticity in the Frog Xenopus laevis
 

Comparative in vivo Study of gp96 Adjuvanticity in the Frog Xenopus laevis

Article DOI: 10.3791/2026
September 16th, 2010

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Summary September 16th, 2010

The frog Xenopus laevis provides an attractive alternative non-mammalian model for exploring the ability of heat shock protein such as gp96 to promote antigen-specific CD8 T cell responses. We present methods to study in vivo facilitation of cross-presentation of skin and tumor antigens by gp96.

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