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JoVE Journal
Biology
Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pip...
Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pip...
JoVE Journal
Biology
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JoVE Journal Biology
Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

Full Text
11,181 Views
10:21 min
July 4, 2007

DOI: 10.3791/225-v

Jason Rasgon1

1Malaria Research Institute, Bloomberg School of Public Health,Johns Hopkins University

In this interview, Jason Rasgon explains the concept of genetic drive and the characteristics of an effective gene drive system. The use of the endosymbiotic bacterium, Wolbachia pipientis, as a means to spread genes through mosquito populations, is hypothesized.

So my name's Dr.Jason Rascon. I'm an assistant professor in the Johns Hopkins Bloomberg School of Public Health in the Department of Molecular Microbiology and Immunology, and also in the Johns Hopkins Malaria Research Institute. And I'm broadly interested in the relationship between the genetics of vector populations and the epidemiology of vector-borne Pathogens.

So malaria Is the most important vector-borne disease in the world today. It's a huge killer. It kills, the stats vary somewhere between one and 3 million people per year.

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