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Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice
This content is Free Access.
Chapters
- 00:05Title
- 01:47Preparation of Infectious Stock of Bioluminescent S. pneumoniae
- 03:14Growth and Preparation of Influenza A Virus Stocks
- 06:22Intranasal Infection of Mice with Bioluminescent S pneumoniae and/or Influenza A Virus
- 07:25Bioluminescent Imaging Using the IVIS Spectrum (Caliper Sciences)
- 09:15In vivo Bioluminescent Imaging of Co-Infection of Respiratory Tract with S. pneumoniae and Influenza Virus
- 10:21Conclusion
A concurrent infection with influenza A virus is one of the factors implicated in the induction of invasive pneumococcal disease during asymptomatic Streptococcus pneumoniae carriage. Here we describe a mixed infection method using infant mice to investigate the synergism between these two respiratory pathogens.
Tags
Bioluminescent ImagingSynergismStreptococcus PneumoniaeInfluenza A VirusInfant Mice1918 Influenza PandemicSecondary Bacterial InfectionPneumococcus1957 Asian Influenza PandemicSeasonal OutbreaksMorbidityConcurrent InfectionMurine ModelInfluenza Virus InfectionS. Pneumoniae ColonizationKineticsIn Vivo Imaging
