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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
This content is Free Access.
Chapters
- 00:05Title
- 04:05Nanomaterial Preparation
- 05:26Methods and Procedures: Animal Preparation
- 07:44Data Acquisition
- 11:10Data Analyses
- 14:12Example Imaging Results
- 15:06Conclusion
Bioimaging methods used to assess cell biodistribution of nanoparticles are applicable for therapeutic and diagnostic monitoring of nanoformulated compounds. The methods described herein are sensitive and specific when assessed by histological coregistration. The methodologies provide a translational pathway from rodent to human applications.
Tags
Registered BioimagingNanomaterialsDiagnostic MonitoringTherapeutic MonitoringNanomedicationsBlood Borne Monocyte-macrophagesReticuloendothelial System (RES)SpleenLiverLymph NodesLungBrainHuman Immunodeficiency Virus Type One (HIV-1) InfectionInflammationMacrophages As NanocarriersSuperparamagnetic Iron-oxide ParticlesDrug Laden ParticlesSurfactantsParenteral InjectionHIV-1 Encephalitic MiceParticle BiodistributionDrug BiodistributionMagnetic Resonance Imaging (MRI)Histological CoregistrationEnhanced Image ProcessingEnd Organ DiseaseAltered Brain HistologyMigration Of NanoformulationsFocal EncephalitisAdvanced Bioimaging TechniquesMacrophage Migration MonitoringHistopathological Aberrations In BrainMRI Studies Of Cell Distribution In Disease
