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JoVE Journal
Bioengineering

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Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells
 

Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells

Article doi: 10.3791/2514
December 2nd, 2010

Summary December 2nd, 2010

Adhesive micropatterns that normalize cellular architecture can be used to increase sensitivity in the detection of drug effects, improve reproducibility and simplify automated image acquisition and analysis. Such technology will benefit drug/siRNA screening assays, performed on conventional cell culture supports and consequently suffering from excessive cell-to-cell variability.

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