This report provides a detailed description of the methodology and results of simultaneous endocardial and epicardial optical mapping of electrical excitation in the intact left atrium of a Langendorff-perfused sheep heart during stretch-induced atrial fibrillation.
Filgueiras-Rama, D., Martins, R. P., Ennis, S. R., Mironov, S., Jiang, J., Yamazaki, M., Kalifa, J., Jalife, J., Berenfeld, O. High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation. J. Vis. Exp. (53), e3103, doi:10.3791/3103 (2011).