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Journal / Medicine / A Simple Guide Screw Method for Intracranial…
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JoVE Journal Medicine
A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice
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A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice

Article DOI: 10.3791/3157-v • 08:12 min • September 26th, 2011
September 26th, 2011 •
1, 2, 1
1Monash Institute of Medical Research, 2MD Anderson Cancer Centre, University of Texas

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In order to evaluate novel therapeutic paradigms for the treatment of glioma, physiological relevant models are essential. We utilize an implantable guide screw procedure for establishment of intracranial xenograft models that is more rapid and safer than stereotactic approaches.

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Intracranial Xenograft Mice Brain Cancers Glioblastoma Medulloblastoma Guide Screw Method Stereotactic Approach Immunosuppressed Mice Tumor Cells Infusion Pump U87MG Glioma Cells AMG102 Antibody HGF/scatter Factor Clinical Evaluation Survival Therapeutic Strategies Brain Cancer Treatment
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