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Immunology and Infection

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JoVE Journal Immunology and Infection
Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
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Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules

Article DOI: 10.3791/3191 • 05:30 min • August 16th, 2011
August 16th, 2011 •
1, 1
1Department of Biology, Case Western Reserve University

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We describe an in vitro method for culturing schistosomula of the flatworm parasite Schistosoma mansoni, via the harvesting and transformation of infective cercariae from the fresh water snail intermediate host Biomphalaria glabrata.

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Cercarial Transformation In Vitro Cultivation Schistosoma Mansoni Schistosomules Schistosomiasis Parasitic Disease Trematode Worms Life Cycle Molluscan Host Mammalian Host Free-swimming Stages Cercariae Secreted Proteases Schistosomules Host Immune System Red Blood Cells Digestion Lungs Portal Circulation Hepatic Portal System Mesenteric Veins Male And Female Worms Pairing And Mating Egg Production Miracidia Snail Species Sporocysts
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