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JoVE Journal
Immunology and Infection

This content is Open Access.

Imaging Leukocyte Adhesion to the Vascular Endothelium at High Intraluminal Pressure
 

Imaging Leukocyte Adhesion to the Vascular Endothelium at High Intraluminal Pressure

Article DOI: 10.3791/3221 06:21 min
August 23rd, 2011

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Summary August 23rd, 2011

This is a method to visualise leukocyte adhesion to the endothelium in harvested pressurised vessels. The technique enables studying vascular adhesion under shear flow with differing intraluminal pressures up to 200 mmHg thus mimic-ing the pathophysiological conditions of high blood pressure.

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