A cyclic pressure bioreactor capable of subjecting heart valve tissue to physiological and pathological pressure conditions has been designed. A LabVIEW program allows users to control pressure magnitude, amplitude and frequency. This device can be used to study the mechanobiology of heart valve tissue or isolated cells.
Schipke, K. J., Filip To, S. D., Warnock, J. N. Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves. J. Vis. Exp. (54), e3316, doi:10.3791/3316 (2011).