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Chapters
- 00:05Title
- 01:33Collection of Colonic Tissue Samples and Assessment of Colitis Severity
- 03:58Sample Preparation for Myeloperoxidase (MPO) Assay
- 05:09Quantification of Inflammatory Markers
- 06:01Evaluating the Severity of Acute Colitis in DSS-treated Animals
- 08:23Conclusion
Experimentele modellen van inflammatoire darmziekte hebben ons de complexe aangeboren en adaptieve immuunrespons geassocieerd met pathogenese te onderzoeken. Met behulp van histologische scoring, kwantificering van pro-inflammatoire cytokines en myeloperoxidase activiteit, kan men beginnen met deze reacties gezien bij inflammatoire darmziekten te beoordelen.
Tags
Intestinal InflammationDSS-induced ModelIBDUlcerative ColitisCrohn’s DiseasePathogenesisGeneticEnvironmental ComponentsAnimal ModelsColonic InflammationDextran Sulphate SodiumColitis-inducing ChemicalsAcute ColitisChronic ColitisWeight LossLoose StoolDiarrheaRectal BleedingHistological AnalysisPro-inflammatory Cytokines
