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A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion
 

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion

Article DOI: 10.3791/3896
July 17th, 2012

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Summary July 17th, 2012

Surgical trauma induces an inflammatory response. Cytokines and endogenous ligands are known to modulate myocardial infarct size following ischemia and reperfusion. We present a modified closed-chest model of murine ischemia and reperfusion using hanging weights to minimize effects of thoracotomy.

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