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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

DOI:
10.3791/3981-v

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10:19 min

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August 09, 2012

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, , , , ,
1Children’s Hospital Boston,Harvard Medical School, 2Tufts University

Chapters

  • 00:05Title
  • 01:25Incision and Exposure of the Bladder
  • 02:43Anastomosis of the Scaffold
  • 04:21Cystostomy Surgery Part 1
  • 07:08Cystostomy Surgery Part 2: Closing the Dorsal Incision
  • 08:43Cystometric Analysis in Alert Animals
  • 09:35Urodynamic Tracing Analysis
  • 09:56Conclusion

Summary

Automatic Translation

Automatic Translation

Surgical stages of bladder augmentation are described using 3-D scaffolds in murine and rat models. To test the efficacy of biomaterial configurations for use in bladder augmentation, techniques for both awake and anesthetized cystometry are presented.

Tags

BiomaterialsBladder AugmentationCystometric AnalysesRodent ModelsRenal FunctionContinence Of UrineUrinary BladderLow PressureContractionCongenital AnomaliesAcquired Urological AnomaliesPosterior Urethral ValvesBenign Prostatic HyperplasiaNeurogenic BladderSpina BifidaSpinal Cord InjuryImpaired ComplianceReduced CapacityUrinary Tract ObstructionUrinary IncontinenceKidney DamageSurgical ImplantationGastrointestinal SegmentsOrgan Capacity ExpansionIntravesical Pressures ReductionComplicationsChronic Urinary Tract InfectionMetabolic PerturbationUrinary Stone FormationSecondary MalignancyBiomaterial Configurations

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