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Assessing Replication and Beta Cell Function in Adenovirally-transduced Isolated Rodent Islets
 

Assessing Replication and Beta Cell Function in Adenovirally-transduced Isolated Rodent Islets

Article DOI: 10.3791/4080
June 25th, 2012

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Summary June 25th, 2012

This protocol allows one to identify factors that modulate functional beta cell mass to find potential therapeutic targets for the treatment of diabetes. The protocol consists of a streamlined method to assess islet replication and beta cell function in isolated rat islets following manipulation of gene expression with adenoviruses.

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