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JoVE Journal
Immunology and Infection
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顆粒球に依存する自己抗体誘発皮膚水疱形成
 
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顆粒球に依存する自己抗体誘発皮膚水疱形成

Article DOI: 10.3791/4250
October 12th, 2012

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Summary October 12th, 2012

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VII型コラーゲンの200アミノ酸(aa 757から967)のストレッチに対してIgG抗体を精製し、我々の現在の仕事で説明する動物モデルで猛烈な表現型だけでなく、人間に特徴的な病理組織および免疫病理学的特徴を再現したマウスに繰り返し注入され後天性表皮水疱症(EBA)

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