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JoVE Journal
Immunology and Infection
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Granulocytt-avhengige autoantistoffer-indusert Skin Blemmer
 
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Granulocytt-avhengige autoantistoffer-indusert Skin Blemmer

Article DOI: 10.3791/4250
October 12th, 2012

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Summary October 12th, 2012

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I dyremodellen beskrevet i vår foreliggende arbeid, renset IgG-antistoffer mot en strekning av 200 aminosyrer (aa 757-967) av kollagen VII er injisert gjentatte ganger i mus reproduserende blistering fenotypen samt histo-og immunopathological funksjoner karakteristiske til menneske Epidermolysis bullosa acquisita (EBA)

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