28,906 Views
•
07:46 min
•
May 09, 2013
DOI:
Summary
Automatically generated
There is accumulating evidence, that ischemic preconditioning (PC) – a non-damaging ischemic challenge to the brain - confers a transient protection to a subsequent damaging ischemic insult. We established bilateral common carotid artery occlusion (BCCAO) as a preconditioning stimulus to induce early ischemic tolerance (IT) to transient focal cerebral ischemia (induced by middle cerebral artery occlusion, MCAO) in C57Bl6/J mice.
Related Videos
09:43
Mouse Model of Middle Cerebral Artery Occlusion
Related Videos
77425 Views
13:01
Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice
Related Videos
49900 Views
07:26
Endothelin-1 Induced Middle Cerebral Artery Occlusion Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Rat
Related Videos
19855 Views
07:43
Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
Related Videos
14868 Views
08:27
Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.
Related Videos
14041 Views
09:11
Embolic Middle Cerebral Artery Occlusion (MCAO) for Ischemic Stroke with Homologous Blood Clots in Rats
Related Videos
26865 Views
09:48
Quantification of Neurovascular Protection Following Repetitive Hypoxic Preconditioning and Transient Middle Cerebral Artery Occlusion in Mice
Related Videos
13677 Views
09:11
Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
Related Videos
21369 Views
10:18
In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium
Related Videos
8940 Views
13:58
A Rabbit Model of Durable Transgene Expression in Jugular Vein to Common Carotid Artery Interposition Grafts
Related Videos
10230 Views
Read Article
Cite this Article
Speetzen, L. J., Endres, M., Kunz, A. Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia. J. Vis. Exp. (75), e4387, doi:10.3791/4387 (2013).
Copy