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JoVE Journal
Behavior

This content is Open Access.

Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET
 

Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking

Article doi: 10.3791/50358
August 6th, 2013

Summary August 6th, 2013

We present a novel PET imaging approach for capturing dopamine fluctuations induced by cigarette smoking. Subjects smoke in the PET scanner. Dynamic PET images are modeled voxel-by-voxel in time by lp-ntPET, which includes a time-varying dopamine term. The results are 'movies' of dopamine fluctuations in the striatum during smoking.

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