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JoVE Journal
Immunology and Infection

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A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
 

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Article doi: 10.3791/50404
July 18th, 2013

Summary July 18th, 2013

This article focuses on the identification of high-confident interaction datasets between host and pathogen proteins using a combination of two orthogonal methods: yeast two-hybrid followed by a high-throughput interaction assay in mammalian cells called HT-GPCA.

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