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JoVE Journal
Biology

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Protein WISDOM
 

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Article DOI: 10.3791/50476 10:58 min
July 25th, 2013

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Summary July 25th, 2013

We developed computational de novo protein design methods capable of tackling several important areas of protein design. To disseminate these methods we present Protein WISDOM, an online tool for protein design (http://www.proteinwisdom.org). Starting from a structural template, design of monomeric proteins for increased stability and complexes for increased binding affinity can be performed.

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