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The In ovo CAM-assay as a Xenograft Model for Sarcoma
 

The In ovo CAM-assay as a Xenograft Model for Sarcoma

Article doi: 10.3791/50522
July 17th, 2013

Summary July 17th, 2013

The in ovo chorioallantoic membrane (CAM) is grafted with fresh sarcoma-derived tumor tissues, their single cell suspensions, and permanent and transient fluorescently labeled established sarcoma cell lines. The model is used to study graft- (viability, Ki67 proliferation index, necrosis, infiltration) and host (fibroblast infiltration, vascular ingrowth) behavior.

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