Journal
/
/
Generering av Subkutan og Intrahepatisk menneskeleverkreft xenografts i immunodeficient Mus
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
DOI:

10:35 min

September 25, 2013

, , , , , , ,

Chapters

  • 00:05Title
  • 01:58Subcutaneous Implantation of Tumor Fragments
  • 02:54Subcutaneous Injection of Tumor Cells
  • 03:23Partial Hepatectomy to Facilitate Intrahepatic Engraftment of Human Tumor Tissue
  • 05:37Intrahepatic Implantation of Tumor Fragments
  • 06:12Intrahepatic Implantation of Tumor Cells via Direct Injection into the Liver
  • 06:52Intrahepatic Xenografting of Tumor Cells via Injection into the Spleen
  • 08:01Results: Representative Intrahepatic Xenograft Images
  • 10:06Conclusion

Summary

Automatic Translation

Menneskelige tumorxenotransplantater i immunodeficient mus er verdifulle verktøy for å studere kreft biologi. Spesifikke protokoller for å generere subkutane og intrahepatiske xenografts fra humane leverkreft celler eller tumor fragmenter er beskrevet. Leveren regenerering indusert ved delvis hepatectomy i mottaker mus er presentert som en strategi for å lette intrahepatisk engraftment.

Related Videos

Read Article