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Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells
 

Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells

Article DOI: 10.3791/50819
January 10th, 2014

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Summary January 10th, 2014

The material here describes a method developed to preserve the three-dimensional chromatin structure of testicular germ cells. This has been termed the three-dimensional (3D) slide method. This method improves sensitivity for detection of subnuclear structures and is applicable for immunofluorescence, DNA, and RNA fluorescence in situ hybridization (FISH).

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