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An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
DOI:

09:02 min

February 17, 2014

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Chapters

  • 00:05Title
  • 01:53Aerosol Infection of Mice with Mycobacterium tuberculosis using a Glas-Col Aerosol Chamber
  • 03:44Verify Uptake of Desired CFU in Lungs
  • 05:05Malaria Infection of Mice by Mosquito Bite
  • 05:50Monitoring Parasitemia
  • 06:47Results: Tuberculosis-Malaria Co-Infection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
  • 08:06Conclusion

Summary

Automatic Translation

Tuberculosis and malaria are two of the most prevalent infections in humans and major causes of morbidity and mortality in impoverished populations in the tropics. We established an experimental model system to study outcome of malaria-tuberculosis coinfection in mice after challenge with both pathogens via their natural route of infection.

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