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Tissue Engineering

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Article DOI: 10.3791/51044-v 09:24 min October 3rd, 2014
October 3rd, 2014



For creation of highly organized structures of complex tissue, one must assemble multiple material and cell types into an integrated composite. This combinatorial design incorporates organ-specific layered cell sheets with two distinct biologically-derived materials containing a strong fibrous matrix base, and endothelial cells for enhancing new vessels formation.


Keywords: Tissue Engineering 3D Scaffold Cell Sheet Multicellular Regeneration Myocardial Infarction Cardiac Tissue Cell Delivery Cell-cell Interactions Matrix Materials PNIPAAM Porous Matrix Hydrogels Endothelial Cells Neovascularization
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