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JoVE Journal
Biology

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Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography
 

Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography

Article DOI: 10.3791/51228
September 14th, 2014

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Summary September 14th, 2014

We present a protocol of how to collect and process electron cryo-tomograms of whole mitochondria. The technique provides detailed insights into the structure, function, and organization of large membrane protein complexes in native biological membranes.

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