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JoVE Journal
Biology

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Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer
 

Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer

Article DOI: 10.3791/51438
May 26th, 2014

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Summary May 26th, 2014

Interactions between proteins are fundamental to all cellular processes. Using Bioluminescence Resonance Energy Transfer, the interaction between a pair of proteins can be monitored in live cells and in real time. Furthermore, the effects of potentially pathogenic mutations can be assessed.

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