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Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer
JoVE Journal
Biology
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JoVE Journal Biology
Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer

Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer

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11:46 min

May 26, 2014

DOI:

11:46 min
May 26, 2014

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Summary

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Interactions between proteins are fundamental to all cellular processes. Using Bioluminescence Resonance Energy Transfer, the interaction between a pair of proteins can be monitored in live cells and in real time. Furthermore, the effects of potentially pathogenic mutations can be assessed.

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