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Biology

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Aip1p Dynamics Are Altered by the R256H Mutation in Actin
 

Aip1p Dynamics Are Altered by the R256H Mutation in Actin

Article doi: 10.3791/51551
July 30th, 2014

Summary July 30th, 2014

Disease-causing mutations in actin can alter cytoskeletal function. Cytoskeletal dynamics are quantified through imaging of fluorescently tagged proteins using total internal fluorescence microscopy. As an example, the cytoskeletal protein, Aip1p, has altered localization and movement in cells expressing the mutant actin isoform, R256H.

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