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Bioengineering

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A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
 

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Article DOI: 10.3791/51797
September 10th, 2014

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Summary September 10th, 2014

We present a microfluidic-based electrochemical biochip for DNA hybridization detection. Following ssDNA probe functionalization, the specificity, sensitivity, and detection limit are studied with complementary and non-complementary ssDNA targets. Results illustrate the influence of the DNA hybridization events on the electrochemical system, with a detection limit of 3.8 nM.

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