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Embolic Middle Cerebral Artery Occlusion (MCAO) for Ischemic Stroke with Homologous Blood Clots in Rats
JoVE Journal
Medicine
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JoVE Journal Medicine
Embolic Middle Cerebral Artery Occlusion (MCAO) for Ischemic Stroke with Homologous Blood Clots in Rats
DOI:

09:11 min

September 17, 2014

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Chapters

  • 00:05Title
  • 01:58Preparation of PE-50 Tube and Homologous Blood Clots
  • 03:24Embolic Middle Cerebral Artery Occlusion
  • 06:37Monitoring Regional Cerebral Blood Flow
  • 07:29Post-operative Care
  • 08:17Results: Embolic Middle Cerebral Artery Occlusion (MCAO) for Ischemic Stroke with Homologous Blood Clots in Rats
  • 08:53Conclusion

Summary

Automatic Translation

In this paper, we demonstrate a standard method for producing an embolic middle cerebral artery occlusion with homologous blood clots (fibrin-rich) in adult rat. This model closely mimics human ischemic stroke and is suitable for preclinical study of thrombolytic therapy for ischemic stroke.

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