26,878 Views
•
09:11 min
•
September 17, 2014
DOI:
Summary
Automatically generated
In this paper, we demonstrate a standard method for producing an embolic middle cerebral artery occlusion with homologous blood clots (fibrin-rich) in adult rat. This model closely mimics human ischemic stroke and is suitable for preclinical study of thrombolytic therapy for ischemic stroke.
Related Videos
06:28
Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model
Related Videos
91365 Views
09:43
Mouse Model of Middle Cerebral Artery Occlusion
Related Videos
77461 Views
13:01
Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice
Related Videos
49919 Views
07:46
Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
Related Videos
28916 Views
07:26
Endothelin-1 Induced Middle Cerebral Artery Occlusion Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Rat
Related Videos
19858 Views
07:43
Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
Related Videos
14873 Views
12:15
Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
Related Videos
23023 Views
08:14
Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
Related Videos
36781 Views
09:48
Quantification of Neurovascular Protection Following Repetitive Hypoxic Preconditioning and Transient Middle Cerebral Artery Occlusion in Mice
Related Videos
13684 Views
09:11
Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
Related Videos
21385 Views
Read Article
Cite this Article
Jin, R., Zhu, X., Li, G. Embolic Middle Cerebral Artery Occlusion (MCAO) for Ischemic Stroke with Homologous Blood Clots in Rats. J. Vis. Exp. (91), e51956, doi:10.3791/51956 (2014).
Copy