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JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Analysis of Cell Migration within a Three-dimensional Collagen Matrix
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Analysis of Cell Migration within a Three-dimensional Collagen Matrix

Article DOI: 10.3791/51963
October 5th, 2014 •
1, 1, 1, 1, 1
1Institute of Immunology & Experimental Oncology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University

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October 5th, 2014

Cell migration is a biological phenomenon that is involved in a plethora of physiological, such as wound healing and immune responses, and pathophysiological processes, like cancer. The 3D-collagen matrix migration assay is a versatile tool to analyze the migratory properties of different cell types within in a 3D physiological-like environment.

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