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Chemistry

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Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
 

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog

Article DOI: 10.3791/52114
November 5th, 2014

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Summary November 5th, 2014

PAD4 is an enzyme responsible for the conversion of peptidyl-arginine to peptidyl-citrulline. Dysregulation of PAD4 has been implicated in a number of human diseases. A facile and high-throughput compatible fluorescence based PAD4 assay is described.

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