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JoVE Journal
Biology

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Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells
 

Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells

Article DOI: 10.3791/52150
December 10th, 2014

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Summary December 10th, 2014

Methods for mapping in vivo protein-DNA interactions are becoming crucial for every aspect of genomic research but they are laborious, costly, and time consuming. Here a commercially available robotic liquid handling system that automates chromatin immunoprecipitation for mapping in vivo protein-DNA interactions with limited amounts of cells is presented.

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