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Protocol for Studying Extinction of Conditioned Fear in Naturally Cycling Female Rats
 

Protocol for Studying Extinction of Conditioned Fear in Naturally Cycling Female Rats

Article DOI: 10.3791/52202
February 23rd, 2015

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Summary February 23rd, 2015

Gonadal hormones such as estrogen modulate memory formation in a number of experimental paradigms including fear extinction memory. This protocol describes a set of methods for investigating the influence of gonadal hormones specifically during extinction in naturally cycling females, including estrous cycle monitoring and exogenous estrogen administration.

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