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JoVE Journal
Medicine

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A Simple Critical-sized Femoral Defect Model in Mice
 

A Simple Critical-sized Femoral Defect Model in Mice

Article DOI: 10.3791/52368
March 15th, 2015

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Summary March 15th, 2015

Animal models are frequently employed to mimic serious bone injury in biomedical research. Due to their small size, establishment of stabilized bone lesions in mice are beyond the capabilities of most research groups. Herein, we describe a simple method for establishing and analyzing experimental femoral defects in mice.

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