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Chemistry

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Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
 

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities

Article doi: 10.3791/52442
May 27th, 2015

Summary May 27th, 2015

Indoxyl glycosides are well-established and widely used tools for enzyme screening and enzyme activity monitoring. Especially for glucose type structures previous syntheses proved to be challenging and low yielding. Our novel approach employs indoxylic acid esters as precious intermediates to yield a considerable number of indoxyl glycosides in good yields.

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