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JoVE Journal
Developmental Biology

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Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans
 

Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans

Article doi: 10.3791/52445
February 22nd, 2015

Summary February 22nd, 2015

We describe the detailed steps of a high-throughput chemical assay in the nematode Caenorhabditis elegans used to assess germline toxicity. In this assay, disruption of germline function following chemical exposure is monitored using a fluorescent reporter specific to aneuploid embryos.

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