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Three-dimensional Co-culture Model for Tumor-stromal Interaction
Three-dimensional Co-culture Model for Tumor-stromal Interaction
JoVE Journal
Medicine
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JoVE Journal Medicine
Three-dimensional Co-culture Model for Tumor-stromal Interaction

Three-dimensional Co-culture Model for Tumor-stromal Interaction

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08:39 min

February 02, 2015

DOI:

08:39 min
February 02, 2015

17316 Views
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Summary

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Here we present a protocol to co-culture in three-dimensions, which is useful for investigating multicellular interactions and extracellular matrix-dependent modulation of cancer cell behavior. In this experimental model, cancer cells are cultured on collagen gels embedded with human cancer-associated fibroblasts.

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