Journal
/
/
Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
DOI:

08:02 min

February 18, 2015

, ,

Chapters

  • 00:05Title
  • 01:19Reconstituting Rag1-deficient Mice with Th17 Cells
  • 02:57Harvesting C. albicans
  • 04:21Mice Infection
  • 06:16TREGs are Required with Th17 to Clear Candida Infections
  • 07:38Conclusion

Summary

Automatic Translation

Although Candida infection models are available to study host immune resistance, a model to study T cell mediated immunopathology in the context of Candida infection is absent. Here we describe a method to establish Th17 immunopathology associated with oral Candida infection in immunodeficient mice.

Related Videos

Read Article