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The Forced Swim Test as a Model of Depressive-like Behavior
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JoVE Journal Behavior
The Forced Swim Test as a Model of Depressive-like Behavior

The Forced Swim Test as a Model of Depressive-like Behavior

DOI:
10.3791/52587-v

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05:42 min

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March 02, 2015

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, , ,
1School of Psychological Sciences,Tel-Aviv University, 2School of Behavioral Sciences,Academic College of Tel Aviv-Yaffo, 3Department of Education and Psychology,The Open University of Israel, 4School of Health and Life Sciences,Hadassah Academic College

Chapters

  • 00:05Title
  • 01:34Preparation for the Forced Swim Test
  • 02:28Training Procedure
  • 03:39The Behavioral Coding
  • 04:28Results: Effect of Treatment on the Forced Swim Test
  • 05:14Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol describes the forced swim test, which is used for the study of depressive-like behavior in rodents. This procedure involves placing an animal in a container filled with water that eventually will lead to the exhibition of immobility behavior, which is considered to reflect behavioral despair.

Tags

Keywords: Forced Swim TestDepressive-like BehaviorRodent ModelBehavioral DespairStressAntidepressant DrugsPredictive ValidityChronic AugmentationBrain Structure/function

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