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Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
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Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

DOI:
10.3791/52598-v

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06:39 min

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April 13, 2015

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, , , , ,
1Cardiac Muscle Research Laboratory, Cardiovascular Division,Brigham and Women’s Hospital, Harvard Medical School, 2Division of Cardiovascular Medicine,Chi-Mei Medical Center, Tainan

Chapters

  • 00:05Title
  • 01:24Long and Short Axis Septal Coronary Artery (SCA) Imaging (B-mode)
  • 02:51Long and Short Axis SCA Imaging (Color Doppler Mode)
  • 03:38Pulse Wave (PW) Doppler Imaging of SCA (Pulsed Wave or PW Mode)
  • 04:34Results: Representative Coronary Flow Analyses
  • 05:45Conclusion

Summary

Automatic Translation

Automatic Translation

Coronary flow reserve (CFR) is useful for assessment of myocardial oxygen demand and evaluation of cardiovascular risk. This study establishes a step-by-step transthoracic Doppler echocardiographic (TTDE) method for longitudinal monitoring of the changes in CFR, as measured from coronary artery in mice, under the experimental pressure overload of aortic banding.

Tags

Keywords: Transthoracic Doppler EchocardiographyCoronary Artery FlowCoronary Flow ReservePressure Overload ModelMiceSeptal Coronary ArteryAortic BandingCoronary Flow VelocitySystolic To Diastolic Peak Velocity RatioNon-invasive AssessmentHistopathology

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