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JoVE Journal
Behavior

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Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
 

Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors

Article DOI: 10.3791/52653 07:54 min
May 10th, 2015

Chapters

Summary May 10th, 2015

Stereotactic injection of lentiviruses expressing cDNAs or shRNAs can modulate gene expression in specific brain areas of mice. Here, we present a protocol to combine stereotactic injections with behavioral tasks, such as the Open Field Test (OFT) and the Forced Swim Test (FST).

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