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Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration
Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration

Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration

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11:43 min

April 03, 2015

DOI:

11:43 min
April 03, 2015

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Summary

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The mechanical properties and microstructure of the extracellular matrix strongly affect 3D migration of cells. An in vitro method to study the spatiotemporal cell migration behavior in biophysically variable environments, at both population and individual cell levels, is described.

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