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Immunology and Infection
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Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination

DOI:
10.3791/52820-v

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10:32 min

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August 24, 2015

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, , , ,
1Terumo BCT,Scientific Affairs

Chapters

  • 00:05Title
  • 02:28Preparation of the Bacterial Suspension
  • 03:29Bacterial Titer
  • 04:48Preparation of the Platelet Product
  • 05:47Riboflavin and UV Light Process
  • 08:34Results
  • 09:16Conclusion

Summary

Automatic Translation

Automatic Translation

The storage conditions of platelet products create an ideal environment for bacterial contaminants to multiply to dangerous levels. The goal of this study was to use a colony forming assay to evaluate a riboflavin based pathogen reduction process against high titer bacterial contamination in human platelet products.

Tags

Keywords: Platelet ProductsRiboflavinUV LightBacterial ContaminationPathogen ReductionLog ReductionS. EpidermidisS. AureusS. MitisS. PyogenesS. MarcescensY. EnterocoliticaB. NeotomaeB. CereusE. ColiP. AeruginosaK. Pneumoniae

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